86-4351-76 INVS Antibody 50ug CSB-PA011769LA01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]特徴
- Background:Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).
仕様
- Aliases:Inversin (Inversion of embryo turning homolog) (Nephrocystin-2), INVS, INV NPHP2
- Product Type:Polyclonal Antibody
- Immunogen Species:Human
- uniprot ID:Q9Y283
- Immunogen:Recombinant Human Inversin protein (1-101AA)
- Host Species:Rabbit
- Species Reactivity:Human
- Tested Applications:ELISA, WB, IHC, IF
- Clonality:Polyclonal
- Isotype:IgG
- Conjugate:Non-conjugated
- Buffer:Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Form:Liquid
- Purification Method:>95%, Protein G purified
- Target Names:INVS
- Research Area:Signal Transduction
- サイズ:50ug
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86-4351-75
INVS Antibody 100ug
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86-4351-76
INVS Antibody 50ug
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