86-4351-25 ［取扱停止］IFIT1 Antibody 100ug CSB-PA011018LA01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]
特徴
- Background：Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group （PPP-RNA）, thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation （cap snatching mechanism）. Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
仕様
- Aliases：Interferon-induced protein with tetratricopeptide repeats 1 （IFIT-1） （Interferon-induced 56 kDa protein） （IFI-56K） （P56）, IFIT1, G10P1 IFI56 IFNAI1 ISG56
- Product Type：Polyclonal Antibody
- Immunogen Species：Human
- uniprot ID：P09914
- Immunogen：Recombinant Human Interferon-induced protein with tetratricopeptide repeats 1 protein （1-181AA）
- Host Species：Rabbit
- Species Reactivity：Human, Mouse, Rat
- Tested Applications：ELISA, WB, IHC, IF
- Clonality：Polyclonal
- Isotype：IgG
- Conjugate：Non-conjugated
- Buffer：Preservative： 0.03％ Proclin 300＜br /＞Constituents： 50％ Glycerol, 0.01M PBS, pH 7.4
- Form：Liquid
- Purification Method：＞95％, Protein G purified
- Target Names：IFIT1
- Research Area：Immunology
- サイズ：100ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4351-25
IFIT1 Antibody 100ug
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86-4351-26
IFIT1 Antibody 50ug
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