86-4344-77 ATP8B1 Antibody 100ug CSB-PA002418LA01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]
特徴
- Background：Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in asymmetric distribution of phospholipids in the canicular membrane. May have a role in transport of bile acids into the canaliculus, uptake of bile acids from intestinal contents into intestinal mucosa or both. In cooperation with ABCB4 may be involved in establishing integrity of the canalicular membrane thus protecting hepatocytes from bile salts. Together with TMEM30A is involved in uptake of the synthetic drug alkylphospholipid perifosine. Involved in the microvillus formation in polarized epithelial cells; the function seems to be independent from its flippase activity. Required for the preservation of cochlear hair cells in the inner ear. May act as cardiolipin transporter during inflammatory injury.
仕様
- Aliases：Phospholipid-transporting ATPase IC （EC 3.6.3.1） （ATPase class I type 8B member 1） （Familial intrahepatic cholestasis type 1） （P4-ATPase flippase complex alpha subunit ATP8B1）, ATP8B1, ATPIC FIC1 PFIC
- Product Type：Polyclonal Antibody
- Immunogen Species：Human
- uniprot ID：O43520
- Immunogen：Recombinant Human Phospholipid-transporting ATPase IC protein （217-330AA）
- Host Species：Rabbit
- Species Reactivity：Human
- Tested Applications：ELISA, IF
- Clonality：Polyclonal
- Isotype：IgG
- Conjugate：Non-conjugated
- Buffer：Preservative： 0.03％ Proclin 300＜br /＞Constituents： 50％ Glycerol, 0.01M PBS, PH 7.4
- Form：Liquid
- Purification Method：＞95％, Protein G purified
- Target Names：ATP8B1
- Research Area：Signal Transduction
- サイズ：100ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4344-78
ATP8B1 Antibody 50ug
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86-4344-77
ATP8B1 Antibody 100ug
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