Background：IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.
Buffer：0.2 um filtered in PBS, pH7.2. Azide Free （AF）/Low Endotoxin （LE）： Contains no stabilizers or preservatives. Endotoxin level is ＜ 2 EU/mg （ ＜ 0.002EU/ug） as Determined by LAL gel clotting assay.
