Background:CD18 is a 95 kD protein, also known as integrin b2 subunit. It is expressed on all leukocytes. CD18, in association with integrin a chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and aXb2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.
Buffer:0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay.