Background：CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1a chain and integrin aL subunit. CD11a non-covalently associates with integrin b2 （CD18） to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 （CD54）, ICAM-2 （CD102）, and ICAM-3 （CD50）.
仕様
Synonyms：Integrin alpha-L,Itgal,CD11 antigen-like family member A,LFA-1A,Lymphocyte antigen 15,Ly-15,CD11a
