Background:CD11c is a 150 kD glycoprotein also known as aX integrin, CR4, and p150. CD11c forms a aXb2 heterodimer with b2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The aXb2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.
仕様
Synonyms:Integrin alpha-X,Itgax,CD11 antigen-like family member C,Leukocyte adhesion receptor p150+95,CD11c