Background：This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.WEE1 （WEE1 G2 Checkpoint Kinase） is a Protein Coding gene. Among its related pathways are PLK1 signaling events and Cell cycle Role of 14-3-3 proteins in cell cycle regulation. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is WEE2.
仕様
Synonyms：DKFZp686I18166,EC 2.7.10.2,FLJ16446,MGC105683,OTTHUMP00000231338,OTTHUMP00000231339,Wee 1,WEE 1 homolog 1 （S. pombe）,WEE1,WEE1 homolog （S. pombe）,Wee1 homolog,WEE1 homolog S. pombe,Wee1 like protein kinase,Wee1 tyrosine kinase,Wee1+ homolog,Wee1+ S. pombe homolog,WEE1,S. pombe,homolog of,WEE1,somatic,Wee1-like protein kinase,WEE1,WEE1A,Wee1A kinase,WEE1hu
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Wee1 around the phosphorylation site of S642.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
Dilution：WB 1：500-1：2000, ELISA 1：5000
Gene_ID（human）：7465
Swissprot：P30291
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
