Background：Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
仕様
Synonyms：1 25 dihydroxyvitamin D3 receptor,1,1,25 dihydroxyvitamin D3 receptor,1,25-@dihydroxyvitamin D3 receptor,25-dihydroxyvitamin D3 receptor,Member 1,NR1I1,Nuclear receptor subfamily 1 group I member 1,PPP1R163,Protein phosphatase 1,regulatory subunit 163,VDR,VDR,Vitamin D （1,25- dihydroxyvitamin D3） receptor,Vitamin D hormone receptor,Vitamin D nuclear receptor variant 1,Vitamin D receptor,Vitamin D3 receptor
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human VDR around the phosphorylation site of S51.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
