Background:This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
仕様
Synonyms:14-3-3-zetaisoform,AI098070,aPKCzeta,C80388,EC 2.7.11.13,KPCZ,nPKC zeta,nPKC-zeta,OTTHUMP00000001368,OTTHUMP00000044160,PKC 2,PKC ZETA,PKC2,Pkcz,PKCZETA,PKM-zeta,included,PRKCZ,Protein kinase C zeta,Protein kinase C zeta form,Protein kinase C zeta type,r14-3-3,R74924,zetaPKC
Host:Rabbit
Reactivity:Human,Mouse,Rat,Monkey
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human PKC ζ around the phosphorylation site of T560.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.