Background：Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
仕様
Synonyms：C-X-C chemokine receptor type 2,CD 182,CD182,CD182 antigen,CDw128b,Chemokine （CXC） receptor 2,CMKAR2,CXC-R2,CXCR 2,CXCR-2,CXCR2,CXCR2,GRO/MGSA receptor,High affinity interleukin-8 receptor B,IL 8 receptor type 2,IL 8R B,IL-8 receptor type 2,IL-8R B,IL8 RB,IL8 receptor type 2,IL8R B,IL8R2,IL8RA,Interleukin 8 Receptor B,Interleukin 8 receptor,beta,Interleukin 8 receptor,type 2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human IL-8Rb around the phosphorylation site of S347.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：10000
Gene_ID（human）：3579
Swissprot：P25025
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
