Background：The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Gab 1,GAB1,GAB1,GRB 2 associated binder 1,GRB 2 associated binding protein 1,GRB2 associated binding protein 1 isoform a,GRB2 associated binding protein 1 isoform b,GRB2-associated binder 1,GRB2-associated-binding protein 1,Growth factor receptor bound protein 2-associated protein 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Gab 1 around the phosphorylation site of Y659.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：5000
Gene_ID（human）：2549
Swissprot：Q13480
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
