Background：The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins （DP）, a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain.
仕様
Synonyms：Dmel￥CG6376,Dmel_CG6376,drosE2F1,E（Sev-CycE）3A,E（var）3-93E,E2-promoter binding facto,E2F 1,E2F transcription factor 1,E2F-1,E2f-PA,E2f-PB,E2f-PC,E2F1,E2f1 E2F transcription factor 1,E2F1,Evar（3）164,KIAA4009,l（3）07172,l（3）j3B1,l（3）j3C2,l（3）rM729,mKIAA4009,OTTHUMP00000030661,PBR3,PRB binding protein E2F 1,PRB-binding protein E2F-1,RBAP 1,RBAP-1,RBAP1,RBBP-3,RBBP3,RBP 3,RBP3,Retinoblastoma-associated protein 1,Retinoblastoma-binding protein 3,Transcription factor E2F1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthetic peptide from human protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 50％ glycerol, pH7.4
Dilution：WB 1：500-10000, ELISA 1：10000
Gene_ID（human）：1869
Swissprot：Q01094
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
