Background:Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214).
仕様
Synonyms:1110034C02Rik,Acute Phase Response Factor,Acute-phase response factor,ADMIO,APRF,AW109958,DNA binding protein APRF,FLJ20882,HIES,MGC16063,Signal transducer and activator of transcription 3 (acute phase response factor),Signal transducer and activator of transcription 3,STAT 3,Stat3,STAT3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human Stat3 around the acetylation site of K87.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, ELISA 1:10000
Gene_ID(human):6774
Swissprot:P40763
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Developmental biology, Signal transduction, Stem cells