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86-4181-57 ［取扱停止］Rabbit anti-Phospho-CASP3 (Ser150) Polyclonal Antibody 20uL RD86219A
86-4181-57 ［取扱停止］Rabbit anti-Phospho-CASP3 (Ser150) Polyclonal Antibody 20uL RD86219A
[Reddot Biotech] Rabbit anti-Phospho-CASP3 (Ser150) Polyclonal Antibody 20uL
特徴
Background：Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly（ADP-ribose） polymerase （PARP） at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins （SREBPs） between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
仕様
Synonyms：A830040C14Rik,Apopain,CASP-3,CASP3,CASP3,Casp3a,Caspase 3,Caspase 3,apoptosis-related cysteine peptidase,Caspase 3,apoptosis-related cysteine protease,Caspase 3,apoptosis-related cysteine protease a,Caspase-3 subunit p12,CC3,CPP-32,CPP32,CPP32B,Cysteine protease CPP32,EC 3.4.22.56,LICE,mldy,OTTHUMP00000165052,OTTHUMP00000165053,OTTHUMP00000165054,PARP cleavage protease,Procaspase3,Protein Yama,SCA 1,SCA-1,SREBP cleavage activity 1,Yama
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Caspase-3 around the phosphorylation site of Ser150
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, ELISA 1：40000
Gene_ID（human）：836
Swissprot：P42574
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Neuroscience
サイズ：20uL
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