Background：Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
仕様
Synonyms：HIST1H2AG,H2AFP,HIST1H2AI,H2AFC,HIST1H2AK,H2AFD,HIST1H2AL,H2AFI,HIST1H2AM,H2AFN,Histone H2A type 1,H2A.1,Histone H2A/p,HIST1H2AB,H2AFM,HIST1H2AE,H2AFA,Histone H2A type 1-B/E,Histone H2A.2,Histone H2A/a,Histone H2A/m,HIS
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Histone H2A around the phosphorylation site of Thr121
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
