Background：On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
仕様
Synonyms：AAT 5,AAT5,Activin A receptor type II like kinase 53kDa,Activin A receptor type II like kinase,53kD,Activin A receptor type II like protein kinase of 53kD,activin A receptor type II-like kinase,53kDa,activin A receptor type II-like protein kinase of 53kD,Activin receptor like kinase 5,Activin receptor-like kinase 5,ACVRLK 4,ACVRLK4,ALK 5,ALK-5,ALK5,LDS1A,LDS2A,MSSE,Serine/threonine protein kinase receptor R4,Serine/threonine-protein kinase receptor R4,SKR 4,SKR4,TbetaR I,TbetaR-I,TGF beta receptor type 1,TGF beta receptor type I,TGF beta type I receptor,TGF-beta receptor type I,TGF-beta receptor type-1,TGF-beta type I receptor,TGFBR 1,TGFBR1,TGFBR1 protein,TGFR 1,TGFR-1,TGFR1,TGFR1,Transforming growth factor beta receptor 1,Transforming growth factor beta receptor I （activin A receptor type II like kinase,53kD）,Transforming growth factor beta receptor I,transforming growth factor,beta receptor 1,transforming growth factor,beta receptor I （activin A receptor type II-like kinase,53kD）,Transforming growth factor-beta receptor type I
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human TGFb RI around the phosphorylation site of Ser165
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-2000, IHC 1：50-300, IF 1：50-300
Gene_ID（human）：7046
Swissprot：P36897
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction, Stem cells
