Background：This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, whicHuman, Mouseediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate （PIP3）, and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仕様
Synonyms：Bmx,BMX non receptor tyrosine kinase,BMX,BONE MARROW KINASE,X-LINKED,Bone marrow tyrosine kinase gene in chromosome X protein,Cytoplasmic tyrosine protein kinase BMX,Cytoplasmic tyrosine-protein kinase BMX,Epithelial and endothelial tyrosine kinase,ETK,NKT38,NTK 38,NTK38,Protein tyrosine kinase BMX,PSCTK 2,PSCTK 3,PSCTK2,PSCTK3
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Bmx around the phosphorylation site of Tyr566
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
