Background:The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.
仕様
Synonyms:47 kDa autosomal chronic granulomatous disease protein,47 kDa neutrophil oxidase factor,NADPH oxidase organizer 2,NCF 47K,NCF-1,NCF-47K,Ncf1,NCF1,Neutrophil cytosol factor 1,Neutrophil cytosolic factor 1,neutrophil cytosolic factor 1,(chronic granulomatous disease,autosomal 1),Neutrophil NADPH oxidase factor 1,Nox organizer 2,Nox organizing protein 2,Nox-organizing protein 2,NOXO2,p47 phox,p47-phox,SH3 and PX domain containing protein 1A,SH3 and PX domain-containing protein 1A,SH3PXD1A
Host:Rabbit
Reactivity:Human
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human p47-phox around the phosphorylation site of Ser359
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Gene_ID(human):653361
Swissprot:P14598
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction