Background:This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability.
仕様
Synonyms:76 kDa tyrosine phosphoprotein,CG8697,LCP 2,LCP2,LCP2,Lymphocyte cytosolic protein 2,SH2 domain containing leukocyte protein 76 KD,SH2 domain containing leukocyte protein of 76kD,SH2 domain containing leukocyte protein of 76kDa,SH2 domain-containing leukocyte protein of 76 kDa,SLP 76,SLP 76 tyrosine phosphoprotein,SLP-76,SLP-76 tyrosine phosphoprotein,SLP76,SLP76 tyrosine phosphoprotein
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human SLP-76 around the phosphorylation site of Tyr128
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4