Background:Apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. Inhibitor of caspase-3, -7 and -9. Mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B.
仕様
Synonyms:AP 13,API3,Apoptosis Inhibitor 3,Baculoviral IAP repeat containing 4,Baculoviral IAP Repeat Containing Protein 4,Baculoviral IAP repeat-containing protein 4,BIRC 4,BIRC4,E3 ubiquitin-protein ligase XIAP,hIAP-3,hIAP3,HILP,IAP 3,IAP like protein,IAP-3,IAP-like protein,IAP3,ILP 1,ILP,ILP1,Inhibitor of apoptosis protein 3,Inhibitor of Apoptosis X Linked,Mammalian IAP Homologue A,MIHA,X linked IAP,X linked inhibitor of apoptosis,X linked inhibitor of apoptosis E3 ubiquitin protein ligase,X linked inhibitor of apoptosis protein,X-linked IAP,X-linked inhibitor of apoptosis protein,Xiap,XIAP,XLP2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human XIAP around the phosphorylation site of Ser87
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4