Background：Receptor for glucocorticoids （GC）. Has a dual mode of action： as a transcription factor that binds to glucocorticoid response elements （GRE） and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone （GH） stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
仕様
Synonyms：GCCR,GCR,GCR,GCRST,glucocorticoid nuclear receptor variant 1,Glucocorticoid receptor,GR,GRL,Grl1,nr3c1,Nuclear receptor subfamily 3 group C member 1,nuclear receptor subfamily 3,group C,member 1 （glucocorticoid receptor）
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human GR around the phosphorylation site of Ser203
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：10000
Gene_ID（human）：2908
Swissprot：P04150
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
