Background：The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis （EL1）. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.EPB41 （Erythrocyte Membrane Protein Band 4.1） is a Protein Coding gene. Diseases associated with EPB41 include Elliptocytosis-1 and Hereditary Elliptocytosis. Among its related pathways are Protein-protein interactions at synapses and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is EPB41L2.
仕様
Synonyms：4.1R,41,Band 4.1,E41P,EL 1,EL1,EL1 gene,Elliptocytosis 1,Elliptocytosis 1 RH linked,EPB 4.1,EPB 41,EPB4.1,Epb41,Erythrocyte membrane protein band 4.1 （elliptocytosis 1 RH linked）,Erythrocyte membrane protein band 4.1,Erythrocyte surface protein band 4.1,HE,P4.1,Protein 4.1,Protein 4.1,red blood cell type
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human 4.1R around the phosphorylation site of Tyr660
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
