Background：This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor （TCF） subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants.ELK3 （ELK3, ETS Transcription Factor） is a Protein Coding gene. Among its related pathways are ID signaling pathway and ERK Signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is ELK4.
仕様
Synonyms：ELK3,ELK3,ETS domain protein （SRF accessory protein 2）,ELK3,ERP,ETS domain protein,ETS domain-containing protein Elk-3,ETS related protein ERP,ETS related protein NET,ETS-related protein ERP,ETS-related protein NET,NET,SAP 2,SAP-2,SAP2,Serum response factor accessory protein 2,SRF accessory protein 2
Host：Rabbit
Reactivity：Human,Mouse,Monkey
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Net around the phosphorylation site of Ser357
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：20000
Gene_ID（human）：2004
Swissprot：P41970
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Immunology
