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86-4180-19 ［取扱停止］Rabbit anti-Phospho-GRK2 (Ser685) Polyclonal Antibody 20uL RD86082A
86-4180-19 ［取扱停止］Rabbit anti-Phospho-GRK2 (Ser685) Polyclonal Antibody 20uL RD86082A
[Reddot Biotech] Rabbit anti-Phospho-GRK2 (Ser685) Polyclonal Antibody 20uL
特徴
Background：Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
仕様
Synonyms：ADRBK1,Adrenergic beta receptor kinase 1,ARBK1,BARK,BARK1,Beta adrenergic receptor kinase 1,Beta ARK 1,Beta ARK1,Beta-adrenergic receptor kinase 1,Beta-ARK-1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,GRK2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human GRK 2 around the phosphorylation site of Ser685
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：5000
Gene_ID（human）：156
Swissprot：P25098
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
サイズ：20uL
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