Background：This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants.TOB1 （Transducer Of ERBB2, 1） is a Protein Coding gene. Among its related pathways are MAPK Signaling： Mitogen Stimulation Pathway and IL-2 Gene Expression in Activated and Quiescent T-Cells. GO annotations related to this gene include transcription corepressor activity and SMAD binding. An important paralog of this gene is TOB2.
仕様
Synonyms：APRO 6,APRO6,MGC104792,MGC34446,PIG 49,PIG49,Proliferation inducing gene 49,Protein Tob1,RP23 244C22.1,TOB 1,Tob 1 protein,TOB,TOB1,Tob1 protein,Transducer of ERBB 2 1,Transducer of erbB 2,Transducer of ERBB2 1,Transducer of erbB2,Trob,TROB 1,TROB1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human TOB1 around the phosphorylation site of Ser164
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
