Background:Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
仕様
Synonyms:AA415432,FLJ21151,GG10 2,GG10_2,KI20A,KIF20A,kinesin family member 20A,Kinesin like protein KIF20A,Kinesin-like protein 174,Kinesin-like protein KIF20A,mitotic kinesin like protein 2,Mitotic kinesin-like protein 2,MKlp2,OTTHUMP00000159481,RAB6 interacting,kinesin like (rabkinesin6),Rab6-interacting kinesin-like protein,RAB6-INTERACTING PROTEIN,KINESIN-LIKE,RAB6KIFL,Rabkinesin 6,Rabkinesin-6
Host:Rabbit
Reactivity:Human
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human KIF20A around the phosphorylation site of Ser528
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4