Background：Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
仕様
Synonyms：Caspase like protein ESPL1,Caspase-like protein ESPL1,ESP 1,ESP1,ESPL 1,Espl1,ESPL1,Extra spindle poles like 1,Extra spindle poles like 1 protein,Extra spindle poles-like 1 protein,FLJ46492,KIAA0165,Separase,Separin,Similar to fission yeast cut1and gene,SSE
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Separase around the phosphorylation site of Ser801
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：40000
Gene_ID（human）：9700
Swissprot：Q14674
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
