Background:Replication protein A 32 kDa subunitis aproteinthat in humans is encoded by theRPA2gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
仕様
Synonyms:60S acidic ribosomal protein P1,AA409079,AI325195,AU020965,ik:tdsubc_2g1,M(2)21C,MGC137236,OTTHUMP00000004008,p32,p34,RCJMB04_6d17 replication protein A2,32kDa,REPA2,Replication factor A protein 2,Replication protein A 32 kDa subunit,Replication protein A 32kDa subunit,Replication protein A 34 kDa subunit,Replication protein A,Replication Protein A2 (32kDa),Replication protein A2,Replication protein A2,32kDa,RF-A protein 2,Rf-A2,RFA,RFA2,RP-A p32,RP-A p34,RP21C,RPA 2,RPA 32,RPA,Rpa2,RPA32,RPA34,RpLP1,RpP2,xx:tdsubc_2g1,zgc:109822
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human RPA p32 around the phosphorylation site of Ser33
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, ELISA 1:10000
Gene_ID(human):6118
Swissprot:P15927
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling