Background：SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' （Mad） and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor （TGF）-beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation.
仕様
Synonyms：SMAD2,MADH2,MADR2,Mothers against decapentaplegic homolog 2,MAD homolog 2,Mothers against DPP homolog 2,JV18-1,Mad-related protein 2,hMAD-2,SMAD family member 2,SMAD 2,Smad2,hSMAD2,SMAD3,MADH3,Mothers against decapentaplegic
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Smad2/3 around the phosphorylation site of Thr8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：10000
Gene_ID（human）：4087/4088
Swissprot：Q15796,P84022
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
