Background：Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor （CD4 being the primary receptor） for HIV-1 R5 isolates.
仕様
Synonyms：AM4 7,C C chemokine receptor type 5,C C CKR 5,C-C chemokine receptor type 5,C-C CKR-5,C-C motif chemokine receptor 5 A159A,CC Chemokine Receptor 5,CC Chemokine Receptor Type 5,CC CKR 5,CC-CKR-5,CCCKR 5,CCCKR5,CCR 5,CCR-5,CCR5,CCR5 chemokine （C C motif） receptor 5,CCR5,CD 195,CD195,CD195 Antigen,Chemokine C C motif receptor 5,Chemokine receptor CCR5,CHEMR13,CKR 5,CKR5,CMKBR 5,CMKBR5,FLJ78003,HIV 1 Fusion Coreceptor,HIV-1 fusion coreceptor,HIV1 fusion coreceptor,IDDM22,MIP-1 alpha receptor
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human CKR-5 around the phosphorylation site of Ser349
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：5000
Gene_ID（human）：1234/727797
Swissprot：P51681
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Microbiology, Neuroscience, Signal transduction
