Background：ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 （integrin alpha-L/beta-2）. During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
仕様
Synonyms：Antigen identified by monoclonal BB2,BB 2,BB2,CD 54,CD_antigen=CD54,CD54,Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1,ICAM1,intercellular adhesion molecule 1 （CD54）,human rhinovirus receptor,Intercellular adhesion molecule 1,Major group rhinovirus receptor,MALA 2,MALA2,MyD 10,MyD10,P3.58,Surface antigen of activated B cells,BB2
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human ICAM-1 around the phosphorylation site of Tyr512
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：40000
Gene_ID（human）：3383
Swissprot：P05362
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Stem cells
