Background：Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones （H2A, H2B, H3 and H4）. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
仕様
Synonyms：CDA07,CDLS5,HD 8,HD8,HDAC 8,Hdac8,HDAC8,HDACL 1,HDACL1,Histone deacetylase 8,Histone deacetylase like 1,MRXS6,RPD 3,RPD3,WTS
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
