Background：May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
仕様
Synonyms：ATP dependent DNA helicase VIII,ATP-dependent DNA helicase VIII,G3BP,G3BP stress granule assembly factor 1,G3BP-1,G3bp1,G3BP1,GAP binding protein,GAP SH3 domain binding protein 1,GAP SH3 domain-binding protein 1,GTPase activating protein （SH3 domain） binding protein 1,hDH VIII,Human DNA helicase VIII,MGC111040,Ras GTPase activating protein binding protein 1,Ras GTPase activating protein SH3 domain binding protein,Ras GTPase-activating protein-binding protein 1,RasGAP associated endoribonuclease G3BP
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human G3BP1 around the phosphorylation site of Ser232
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
