Background：DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.
仕様
Synonyms：Docking protein 2 56kDa,Docking protein 2,DOK 2,DOK R,DOK2,DOK2,Downstream of tyrosine kinase 2,OTTHUMP00000161710,OTTHUMP00000224923,p56（dok 2）,p56（dok-2）,p56dok 2,p56DOK,p56dok2
Host：Rabbit
Reactivity：Human,Mouse,Monkey
Applications：WB,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Dok-2 around the phosphorylation site of Tyr299
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IF 1：100-1：300, ELISA 1：20000
