Background:Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
仕様
Synonyms:erythroid derived 2,HEBP1,like 2,NF E2 related factor 2,NF-E2-related factor 2,NF2L2,NFE2 related factor 2,NFE2-related factor 2,Nfe2l2,Nrf 2,NRF2,Nuclear factor (erythroid derived 2) like 2,Nuclear factor,nuclear factor erythroid 2 like 2,Nuclear factor erythroid 2 related factor 2,Nuclear factor erythroid 2-related factor 2,Nuclear factor erythroid derived 2 like 2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4