Background：The protein encoded by this gene mediates leucine-rich nuclear export signal （NES）-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
仕様
Synonyms：Chromosome region maintenance 1 protein homolog,CRM 1,CRM1 homolog,DKFZp686B1823,emb,Exp 1,Exp1,Exportin 1,Exportin-1,Exportin1,XPO 1,xpo1,XPO1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human CRM1 around the acetylation site of K568.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：10000
Gene_ID（human）：7514
Swissprot：O14980
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
