Background:This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.
仕様
Synonyms:CCS 3,CCS3,Cervical cancer suppressor 3,chunp6927,CTCL tumor antigen,EE1A1,EEF 1,EEF1A,eEF1A-1,EEF1A1,EF-1-alpha-1,EF-Tu,EF1A,EF1a like protein,EF1A1,Elongation factor 1 alpha subunit,Elongation factor 1-alpha 1,Elongation factor Tu,Eukaryotic elongation factor 1 A-1,Eukaryotic translation elongation factor 1 alpha 1,Eukaryotic translation elongation factor 1 alpha 1 like 14,Glucocorticoid receptor AF 1 specific elongation factor,GRAF 1EF,HNGC:16303,ik:tdsubc_2a3,ik:tdsubc_2b3,LENG7,Leukocyte receptor cluster (LRC) member 7,Leukocyte receptor cluster member 7,Prostate tumor inducing protein 1,PTI1,tdsubc_2a3,Translation elongation factor 1 alpha 1 like 14,wu:fa91c07,wu:fa94b03,wu:fi13b09,xx:tdsubc_2a3,xx:tdsubc_2b3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the human EF-1 a1/2 around the acetylation site of K41.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, ELISA 1:20000
Gene_ID(human):1915
Swissprot:P68104
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling