Background：Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
仕様
Synonyms：HIST1H2BA,TSH2B,Histone H2B type 1-A,Histone H2B,testis,Testis-specific histone H2B,HIST1H2BB,H2BFF,Histone H2B type 1-B,Histone H2B.1,Histone H2B.f,H2B/f,HIST1H2BC,H2BFL,HIST1H2BE,H2BFH,HIST1H2BF,H2BFG,HIST1H2BG,H2BFA,HIST1H2BI,H2BFK
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human Histone H2B around the acetylation site of K5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：10000
Gene_ID（human）：54145
Swissprot：P57053
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
