Background：MAPK14（mitogen-activated protein kinase 14） is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T（H）17 differentiation and inflammation（PMID：22231518）. It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell（PMID：21198398）. This protein has 4 isoforms produced by alternative splicing.
仕様
Synonyms：CSAID Binding Protein 1,CSAID binding protein,CSAID-binding protein,Csaids binding protein,CSBP 1,CSBP 2,CSBP,CSBP1,CSBP2,CSPB1,Cytokine suppressive anti-inflammatory drug-binding protein,EXIP,MAP kinase 14,MAP kinase MXI2,MAP kinase p38 alpha,MAPK 14,MAPK14,MAX interacting protein 2,MAX-interacting protein 2,Mitogen Activated Protein Kinase 14,Mitogen activated protein kinase p38 alpha,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase p38 alpha,MK14,Mxi 2,MXI2,p38 ALPHA,p38,p38 MAP kinase,p38 MAPK,p38 mitogen activated protein kinase,p38ALPHA,p38alpha Exip,PRKM14,PRKM15,RK,SAPK2A
Host：Mouse
Reactivity：Human,Mouse,Rat
Applications：IHC-p
Concentration：1mg/mL
Immunogen：Synthetic Peptide of P38
Purification Method：Protein A purification
Clonality：Monoclonal
Clone No.：1G1
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide and 50％ glycerol pH 7.4.
Dilution：IHC 1：50-300
Gene_ID（human）：1432
Swissprot：Q16539
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction
