Background：Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
仕様
Synonyms：I kappa B beta,I-kappa-B-beta,IkappaBbeta,IKB beta,IkB-B,IkB-beta,IKBB,IKBB,IkBbeta,NF kappa BIB,NF-kappa-B inhibitor beta,NF-kappa-BIB,Nfkbib,Thyroid receptor interacting protein 9,Thyroid receptor-interacting protein 9,TR interacting protein 9,TR-interacting protein 9,TRIP-9,TRIP9
Host：Mouse
Reactivity：Human,Mouse,Rat
Applications：IHC-p
Concentration：1mg/mL
Immunogen：Recombinant Protein
Purification Method：Protein A purification
Clonality：Monoclonal
Clone No.：NAL4
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
Dilution：IHC 1：100-200
Gene_ID（human）：4793
Swissprot：Q15653
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
