Background：ATG7 （Autophagy Related 7） is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Innate Immune System. GO annotations related to this gene include protein homodimerization activity and ubiquitin activating enzyme activity. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：1810013K23Rik,Apg 7,APG7 autophagy 7 like,APG7 autophagy 7-like （S. cerevisiae）,APG7 like,APG7,S. cerevisiae,homolog of,APG7-like,APG7L,ATG 7,ATG12-activating enzyme E1 ATG7,ATG7,ATG7 autophagy related 7 homolog （S. cerevisiae）,ATG7 autophagy related 7 homolog,ATG7,Atg7l,Autophagy 7,S. cerevisiae,homolog of,Autophagy related protein 7,Autophagy-related 7 （yeast）,Autophagy-related protein 7,DKFZp434N0735,GSA 7,GSA7,hAGP7,Ubiquitin activating enzyme E1 like protein,Ubiquitin-activating enzyme E1-like protein,Ubiquitin-like modifier-activating enzyme ATG7
Host：Mouse
Reactivity：Human,Mouse,Rat
Applications：IHC-p,IF
Concentration：1mg/mL
Immunogen：Recombinant Protein of ATG7
Purification Method：Protein A purification
Clonality：Monoclonal
Clone No.：1A1
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 50％ glycerol, pH7.4
Dilution：IHC 1：50-300, IF 1：50-1：200
Gene_ID（human）：10533
Swissprot：O95352
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
