Background:Autophagy protein 5is aproteinthat in humans is encoded by theATG5gene. It is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
仕様
Synonyms:APG 5,APG 5L,APG5,APG5 autophagy 5 like,APG5 like,APG5-like,APG5L,Apoptosis specific protein,Apoptosis-specific protein,ASP,ATG 5,Atg5,ATG5 autophagy related 5 homolog,ATG5,Autophagy protein 5,Autophagy related 5,hAPG5,Homolog of S Cerevisiae autophagy 5,OTTHUMP00000040507
Host:Mouse
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p
Concentration:1mg/mL
Immunogen:Recombinant Protein of ATG5
Purification Method:Protein A purification
Clonality:Monoclonal
Clone No.:5D3
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Dilution:WB 1:500-2000, IHC 1:50-300
Gene_ID(human):9494
Swissprot:Q9H1Y0
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction