Background:The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2.
仕様
Synonyms:ATG8F,Autophagy-related protein LC3 B,Autophagy-related ubiquitin-like modifier LC3 B,LC3B,LC3II,MAP1 light chain 3 like protein 2,MAP1 light chain 3-like protein 2,MAP1A/1BLC3,MAP1A/MAP1B LC3 B,MAP1A/MAP1B light chain 3 B,MAP1ALC3,MAP1LC3B a,Map1lc3b,Microtubule associated protein 1 light chain 3 beta,Microtubule-associated protein 1 light chain 3 beta,Microtubule-associated proteins 1A/1B light chain 3B,MLP3B
Host:Mouse
Reactivity:Human
Applications:IHC-p
Concentration:1mg/mL
Immunogen:Recombinant Protein of LC3B of MAP1LC3B
Purification Method:Protein A purification
Clonality:Monoclonal
Clone No.:6E4
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:IHC 1:100-200
Gene_ID(human):81631
Swissprot:Q9GZQ8
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction