Background：Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
仕様
Synonyms：Apoptosis regulator BAX,BAX,Bax-protein,BAX,BAXA,Baxdelta2G9,Baxdelta2G9omega,Baxdelta2omega,Bcl-2-like protein 4,BCL2 associated X protein,BCL2 associated X protein omega,BCL2 associated X protein transcript variant delta2,Bcl2-L-4,BCL2L4,membrane isoform alpha
Host：Mouse
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p
Concentration：1mg/mL
Immunogen：Synthetic Peptide of Bax
Purification Method：Protein A purification
Clonality：Monoclonal
Clone No.：1D8
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
