Background:This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.
仕様
Synonyms:Active transcription factor CREB,cAMP response element binding protein 1,cAMP response element binding protein,cAMP responsive element binding protein 1,cAMP-responsive element-binding protein 1,CREB,CREB-1,CREB1,CREB1,Cyclic AMP-responsive element-binding protein 1,MGC9284,OTTHUMP00000163864,OTTHUMP00000163865,OTTHUMP00000206660,OTTHUMP00000206662,OTTHUMP00000206667,Transactivator protein
Host:Mouse
Reactivity:Human,Mouse
Applications:WB,IHC-p
Concentration:1mg/mL
Immunogen:Recombinant Protein
Purification Method:Protein A purification
Clonality:Monoclonal
Clone No.:3F1
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Dilution:WB 1:500-1000, IHC 1:100-200
Gene_ID(human):1385
Swissprot:P16220
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology