Background：The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B （PRB） is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A： inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4： Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.
仕様
Synonyms：NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PRA,PRB,PRGR,Progesterone receptor,Progestin receptor form A,Progestin receptor form B
Host：Mouse
Reactivity：Human,Mouse,Rat
Applications：IHC-p,IF
Concentration：1mg/mL
Immunogen：Synthetic Peptide
Purification Method：Protein A purification
Clonality：Monoclonal
Clone No.：1A5
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 50％ glycerol, pH7.4
Dilution：IHC 1：100-1：300, IF 1：100-200
Gene_ID（human）：5241
Swissprot：P06401
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction
