Background:This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:GIG12,Growth inhibiting protein 12,HLF2,Kaliocin 1,Lactoferrin,Lactoferroxin-C,Lactotransferrin,LF,LTF,Neutrophil lactoferrin,Talalactoferrin,TRFL
Host:Mouse
Reactivity:Human
Applications:IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthetic Peptide
Purification Method:Protein A purification
Clonality:Monoclonal
Clone No.:1A6
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Dilution:IHC 1:50-300, IF 1:50-1:200, ELISA 1:5000-10000