Background:This gene encodes a member of the EF-hand super family of calcium binding proteins, which are involved in a variety of cellular processes including mitosis, synaptic transmission, and cytoskeletal rearrangement. The protein encoded by this gene is composed of an N-terminal disordered region, proline-rich elements, two EF-hands, and a C-terminal coiled-coil domain. This protein has been shown to associate with the mitochondrial inner membrane, and in HeLa cells, acts as a novel mitochondrial calcium ion sensor for mitochondrial flash activation. Alternative splicing results in multiple transcript variants.EFHD1 (EF-Hand Domain Family Member D1) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is EFHD2.
仕様
Synonyms:4931430I01Rik,AI452351,DKFZp781H0842,,EF hand domain containing 1,EF hand domain family,member D1,EF-hand domain-containing protein 1,EF-hand domain-containing protein D1,EFHD1,EFHD1,FLJ13612,MGC103094,Mitocalcin,MST133,MSTP133,PP3051,RGD1559565,Swiprosin 2,Swiprosin-2,SWS2
Host:Mouse
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF
Concentration:1mg/mL
Immunogen:Synthetic Peptide
Purification Method:Protein A purification
Clonality:Monoclonal
Clone No.:5K1
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Dilution:WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:200