Background:This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
仕様
Synonyms:DKFZp686I2148,MAP 2,MAP dendrite specific,MAP-2,MAP2,MAP2A,MAP2B,MAP2C,Microtubule associated protein 2,Microtubule-associated protein 2,MTAP2
Host:Mouse
Reactivity:Human,Mouse,Rat
Applications:IHC-p,IF
Concentration:1mg/mL
Immunogen:Synthetic Peptide
Purification Method:Protein A purification
Clonality:Monoclonal
Clone No.:5F2
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Dilution:IHC 1:100-1:300, IF 1:50-200
Gene_ID(human):4133
Swissprot:P11137
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction, Stem cells